Indications: Mucuna contains L-DOPA which is a neurotransmitter precursor, an effective herb for relief in Parkinson’s disease. In a 1995 study, Hp-200 (derived from the Ayurvedic therapeutic agent Mucuna prurient seed powder, as opposed to isolated active ingredients) was tested on 60 patients suffering from Parkinson's disease for 12 weeks. A control sample of 26 patients were given synthetic treatments. The results were monitored with the Unified Parkinson's Disease Rating Scale. The study showed that the Ayurvedic treatment was effective and only caused minor side effects. Mucuna is also useful in increasing sperm count in men and ovulation in women.. It prevents male and female sterility and acts as a nervine tonic. Ayurvedic Applications: Seeds: One of the best tonics and aphrodisiacs for the reproductive system. Indigestion, colic, debility, edema, impotence, infertility, leukorrhea, menorrhagia, roundworm, spermatorrhea, Parkinson’s. Generally, this herb is used with Amalaki, Ashwagandha, Shatavari, Gokshura, white and black musali to make pills and jellies.Roots-fever, edema, elephantiasis (externally), nervous disorders, including facial paralysis Herbal Actions: The total alkaloids from seeds of Mucuna pruriens comprising 5 alkaloidal bases were found to bring about a note-worthy increase in the population of spermatozoa and in the weights of body testes, seminal vesicles and prostrate of the treated rats. The exhibited activity was found to stimulate testosterone-enanthate induced androgenic activity observed in another set of treated individuals. (Saksena, S. and Dixit, V.K., Ind. J. Nat. Prod, 1987, 3(1), 3-7). Lower dose corresponding to the clinical dose significantly decreased the sleeping time, increased the motor activity and gave equivocal results in rotarod test in experimental animals. The high dose (3 times the clinical dose) significantly increased the sleeping time, decreased the motor activity and reduced the time for falling from the rod. Thus the drug possesses CNS stimulant effect at low doses and CNS depressant effect at high doses. (Ahmad, S., et al., Conference of Pharmacology and Symposium of Herbal Drugs. (New Delhi), March 1991, 15, 26.) A seed diet produced a hypoglycemic effect in normal rats, however, such a diet had an insignificant effect on alloxan-treated rats (Pariksh et al, Indian Drugs, 1990, 27, 353; Gopal, J Econ Taxon Bot, 1991, 15, 677; Handa et al, Fitorerapia, 1989, 60, 210). Traditional Uses: Toasted ground seeds are used as a coffee substitute (RVM). Elsewhere regarded as anodyne, antidotal aphrodisiac, diuretic, nervine, resolvent, rubefacient, and vermifuge; used for anasarca, asthma, cancer, cholera, cough, diarrhea, dogbite, dropsy, dysuria, insanity, mumps, pleuritis, ringworm, snakebite, sores, syphilis, tumors, and worms (DAW). Interesting that this reputedly aphrodisiac plant should contain l-doipa, side effects of which include priapism (JAD). Mucuna pruriens, commonly known as velvet bean or cow itch, is a plant indigenous to India A clinical study confirmed the efficacy of the seeds in the management of Parkinson’s disease by virtue of their L-dopa content1. Mucuna pruriens, recognized as an aphrodisiac in Ayurveda, has been shown to increase testosterone levels, leading to deposition of protein in the muscles and increased muscle mass and strength. The extract is also known to enhance mental alertness and improve coordination. Contraindications: Adverse effects were mild and were mainly gastro-intestinal in nature. No adverse effects were seen in clinical laboratory reports (lbid, 1995).. Ingredients: Standardized extract of Mucuna - 15% L-Dopas Other Ingredients: Capsule (vegetable cellulose), 100% vegetarian. No fillers, binders or common allergens. Servings Per Container: 60 vegetarian capsules 500 mg. each Suggested use: One capsule two times daily or as directed by your physician |
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